Transcriptomic response of Anopheles gambiae sensu stricto mosquito larvae to Curry tree (Murraya koenigii) phytochemicals
نویسندگان
چکیده
منابع مشابه
Methanolic extract of Agerantum conyzoides exhibited toxicity and growth disruption activities against Anopheles gambiae sensu stricto and Anopheles arabiensis larvae
BACKGROUND Vector control remains the mainstay to effective malaria management. The negative implications following persistent application of synthetic insecticides geared towards regulation of mosquito populations have necessitated prospection for ecofriendly effective chemistries. Plant-derived compounds have the potential to control malaria-transmitting mosquito populations. Previously, Ager...
متن کاملTranscriptomic insight into terpenoid and carbazole alkaloid biosynthesis, and functional characterization of two terpene synthases in curry tree (Murraya koenigii)
Curry tree (Murraya koenigii L.) is a rich source of aromatic terpenes and pharmacologically important carbazole alkaloids. Here, M. koenigii leaf transcriptome was generated to gain insight into terpenoid and alkaloid biosynthesis. Analysis of de novo assembled contigs yielded genes for terpene backbone biosynthesis and terpene synthases. Also, gene families possibly involved in carbazole alka...
متن کاملSusceptibility to three pyrethroids and detection of knockdown resistance mutation in Ghanaian Anopheles gambiae sensu stricto.
Although insecticides play a crucial role in malaria control programs, this strategy is threatened by the development of resistance in the vectors to commonly used public health insecticides. Due to their known efficacy and lower toxicity to humans and non-target organisms, pyrethroids have been used in many vector control projects. In West Africa, pyrethroid resistance in the major malaria vec...
متن کاملEffective population size in relation to genetic modification of Anopheles gambiae sensu stricto
Effective population size (Ne) is a single number which allows us to relate a large part of population-genetics theory built around ideal populations to real populations. In the case of Anopheles gambiae, Ne is important to interpreting the temporal and spatial distribution of genes. These patterns are in turn used to explore the structure of (typically non-ideal) natural populations. We discus...
متن کاملAssessment of Quality of Curry Leaves (Murraya koenigii)
Murraya koenigii is a valuable medicinal plant which has been used in traditional system of medicine since long time. The extraction of active ingredients such as alkaloids, flavonoids, triterpenes, steroids etc. from the plant facilitates pharmacological studies. The present investigation is to evaluate the proper taxomic status and preliminary phyto-chemical characters as well as physicochemi...
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ژورنال
عنوان ژورنال: Parasites & Vectors
سال: 2021
ISSN: 1756-3305
DOI: 10.1186/s13071-020-04505-4